Alzheimer's: Four New Discoveries of 2016

by: Tyler Frasher

1. Aducanumab

Aducanumab is an antibody that has shown promise in attacking the amyloid plaques. These plaques form between the nerve cells of those who are affected by the disease. A double-blind, four-year trial was conducted on patients with moderate disease indicators where they were infused with the antibody. This infusion showed marked improvement in the symptoms of the disease.

2. Indicative Gene Signatures
Younger people with a particular gene signature can show a risk for Alzheimer’s early in life according to a group of researchers. This signature makes the brain more susceptible to the proteins that form in the condition that cause the damaging plaque buildup.

3. Fast Tracking BACE Inhibitors

AZD3293, a drug, has also shown promise in treating mild to moderate cases of the condition. This is done so by reducing the amount of amyloid buildup around the neurons. However, this drug has been fast-tracked and is nowhere near ready for use as a successful treatment.

4. Intensive Research
A group of researchers at Sutter Neuroscience Institute have been working with five methods to combat the disease as opposed to just one. The use of the intravenous immunoglobulin antibodies, the effects of vitamin D on memory, and the ethnic implications of Alzheimer’s are all under investigation as methods to combat the disease.


Sources:
http://dailynurse.com/four-new-alzheimers-discoveries-2016/